Women and Cancer
Women and Cancer
advertisement
top
bottom
The War Room
The War Room Therapeutic Advances and Drugs in the News

The latest developments in treatment and research play a central role in each issue of Women&Cancer. We want our readers to know what therapies are available and what drugs may be an option in the future so that they can make informed, empowered decisions about their own health and the health of their loved ones.

We feel that the in-depth articles describing advances in treatment and the current research news are best illustrated by real-life stories of women who have felt the impact of a cancer diagnosis themselves, so throughout the section we take care to share personal stories of survivorship and advocacy. The women whose journeys are highlighted on these pages give real meaning to the advances that are being made in cancer treatment today, and “The War Room” is brought to life by their stories.

Fall 2009 Articles
complimentary
Staying a Step Ahead
The decision of whether to undergo prophylactic mastectomy is personal for women who test positive for BRCA1 and BRCA2.
Where Cancer Meets Culture
Addressing cancer among the nation’s Latino population requires awareness of its unique impact among these communities as well as cultural sensitivity.
The HERA Women’s Cancer Foundation
As one of the earliest symbols of empowerment for women, Hera—the goddess of women in Greek mythology and the wife of Zeus—plays a powerful role in the history of feminism.
Couples Cope with Cancer
If your partner has been diagnosed with cancer, there are strategies and resources to help you through.
Long-term Androgen Suppression Is Superior for Prostate Cancer
Long-term Androgen Suppression Is Superior for Prostate Cancer Short-term androgen suppression produces inferior survival compared with long-term androgen suppression in the treatment of locally advanced prostate cancer.
Forging Ahead: Recent Advances in the Fight Against Ovarian Cancer
On Christmas Day 1809, Jane Todd Crawford had an astonishing 22-pound tumor extracted from her abdomen.
Heartbreak and Hope
Women share stories of genetic testing.
Ovarian Cancer Research Fund
Ovarian cancer is not a cancer that individuals are necessarily familiar with,”says Elizabeth Howard, chief executive officer of the Ovarian Cancer Research Fund (OCRF). As a result, “women are quite taken aback when they are told they have [the disease].”
Addition of Vectibix to First-line Chemotherapy Improves Progression-free Survival in Metastatic Colorectal Cancer
Among patients with metastatic colorectal cancer, the addition of the targeted therapy Vectibix® (panitumumab) to chemotherapy delayed cancer progression.
Breast Cancer Highlights from the 2009 Annual Meeting of the American Society of Clinical Oncology
The 45th Annual Meeting of the American Society of Clinical Oncology (ASCO), held May 29 to June 2, 2009, in Orlando, Florida, brought together an estimated 20,000 cancer specialists. The studies presented at the meeting addressed topics ranging from prevention and early detection through treatment and survivorship.
Additional Articles
VBeacons in the Night
Researchers, clinicians, and survivors whose work and lives are daily informed by their experience in the young survivor community share information and insight for young women facing breast cancer.
Vanquishing Virus-associated Cancers
Human papillomaviruses have a wide range of health effects, but vaccines continue to offer hope for prevention.
Pancreatic Cancer Action Network
Human Julie Fleshman knows all about the urgent need for hope that grips people facing a pancreatic cancer diagnosis; in 1999 her father was diagnosed with the disease at age 52 and passed away four months later. papillomaviruses have a wide range of health effects, but vaccines continue to offer hope for prevention.
New Developments in Kidney Cancer Treatment
Cancer was the farthest thing from Daryl O’Brien’s mind when she went for a routine OB/GYN exam in the fall of 1996. A 40-year-old pediatrician and mother of three children then ages four, seven, and nine, she had recently had a physical and been declared “perfectly healthy.”
Set the Date…for Cancer Screenings
Screening guidelines should initiate conversations with your healthcare team.
Cancer and Fertility
Questions to ask before and after cancer treatment
War Room News
Skin Cancer: What You Need to Know Now
Prevention and early detection are the keys.
An Unhealthy Glow
Indoor tanning is a $5 billion–per–year industry that’s marketed itself as safe and even beneficial. The truth may not be so sunny.
Melanoma Research Alliance
Melanoma survivor Debra Black and her husband, Leon, had a singular purpose when they founded the Melanoma Research Foundation.
Updates from the 2008 San Antonio Breast Cancer Symposium
Breast Implants: What We Now Know
Breast implants have been the subject of much debate. Here’s what we know.
Lung Cancer: Still Number One
Lung cancer remains the leading cause of cancer death in both men and women.
One Survivor Steps Up
Lung cancer survivor Bonnie Addario strives to leave a legacy of hope.
Lung Cancer Alliance
Laurie Fenton Ambrose, president and CEO of the Lung Cancer Alliance (LCA)
War Room News
It’s in the Genes News
Katie Couric
The CBS News anchor and managing editor describes her personal story and her passionate commitment to colon cancer advocacy.
The Other Women’s Cancer
An update on screening, diagnosis, and treatment options for colorectal cancer
Advancements in Screening for Colorectal Cancer
New technologies aim to increase compliance rates and save lives
The Colon Club
Meet an organization defined by out-of-the-box projects that inspire lifesaving dialogue and a thriving support community.
The War Room News
• FDA Approves New Test to Detect HER2 Status in Breast Cancer
• Addition of Avastin to Taxotere Improves Progression-free Survival in Advanced Breast Cancer
It's in the Genes News
Oncotype DX Accurately Determines HER2 Status in Breast Cancer
Thyroid Cancer: It’s Not in Your Head—It’s in Your Neck!
It all started with bumps—what I would later learn were actually called nodules—in my neck.
Cancer Vaccines to Watch
At least a dozen cancer treatment vaccines are currently being tested in advanced clinical trials. Here’s a look at a few you may be hearing more about in the near future.
Abundantly Blessed
Good Morning America’s Robin Roberts, who has spent the past year sharing her breast cancer journey with viewers, describes the inspiration and the challenges of facing a diagnosis in the public eye.
Breast Cancer Survivorship 101
You’ve completed treatment for breast cancer, and you’ve been told it’s time to look ahead. But what do you need to know to navigate this new part of the cancer journey?
Living to Thrive
Olivia Newton-John embraces the busy life that allows her to be an advocate, a performer, and a force for positive change.
Walking In Our Patients Shoes
What we can learn from women health professionals who develop breast cancer
Breast Cancer Advocacy
Y-ME/Breast Cancer Network of Strength celebrates 30 years of empowering breast cancer survivors.
Raise a glass or set it down?
Alcohol and Women’s Health
Genetic Testing For Women at High Risk of Ovarian Cancer
When risk is assessed appropriately and testing is managed effectively, genetic testing for BRCA1 and BRCA2 mutations can provide patients at risk of ovarian cancer with information, options, and ultimately empowerment.
The Gynecologic Oncology Group: Advancing The Prevention And The Treatment Of Gynecologic Cancers
The Gynecologic Oncology Group (GOG), established in 1970 by a group of gynecologic surgeons interested in promoting a “collaborative research effort, not only among institutions but also among the various disciplines involved in the treatment of women with gynecologic cancers.”
A Mother's legacy
The Lynne Cohen Foundation for Ovarian Cancer Research
The War Room News
• Targeted Therapy with Tykerb and Herceptin Improves Survival of Patients with Advanced Breast Cancer
• FDA Approves Non-anthracycline Chemotherapy Regimen plus Herceptin for Early Breast Cancer
Cancer Vaccines
Using the body's own defense system to eradicate disease and prevent future occurrence, these new therapies show promise.
Taking a Shot at Cervical Cancer
HPV vaccines continue to offer hope for prevention.
Reconstruction Advances
The latest advances in implants and autogenous tissue breast reconstruction offer women more options as they face mastectomy and reconstruction choices.
Reproductive Concerns and Cancer Treatment: What You Need to Know
The latest advances in implants and autogenous tissue breast reconstruction offer women more options as they face mastectomy and reconstruction choices.
Involuntary and Far from Innocuous: The Health Effects of Secondhand Smoke
There is no safe level of exposure to secondhand smoke, and the evidence of adverse effects on health is incontrovertible.
The War Room News
• Femara May Protect Against Breast Cancer Years After Tamoxifen
• Cancer Rates Stabilize but More Work to Be Done in 2008
• Avastin Approved for Advanced Breast Cancer
• FDA Approves New Genetic Test for Breast Cancer Patients
• Oncotype DX Added to NCCN Guidelines
Cover Up!
Sun protection products offering comfort and style
Simple Screening for a Deadly Disease
Thanks to recent media campaigns, at this point most of us have heard the message that spending time in the midday sun without protection is not a good idea. At some point in our lives, however, the majority of us have broken the rules, either intentionally going after that deadly tan or at the very least spending brief periods outside while forgetting to protect ourselves from the sun.
Treatment of Nonmelanoma Skin Cancer
Each year in the United States, more than one million people are diagnosed with basal cell or squamous cell skin cancers.
More Than Skin Deep
When Skin Cancer Requires Surgery and Reconstruction
The Skin Cancer Foundation
When Dr. Perry Robins founded the Skin Cancer Foundation in 1979, the fledgling advocacy organization faced major obstacles
Getting Your Head Around Brain Cancer
Understanding this complex disease and its treatment options
Brain Tumor Advocacy Groups
"There's not a typical brain tumor survivor," says Sarah Gupta, LICSW
Advances In Breast Cancer Treatment
A Report from the 2007 Annual San Antonio Breast Cancer Symposium
A Special Kind of Sisterhood
A group of HER2-positive survivors in Bakersfield, California, come together to empower one another and inform the public about their disease.
The War Room News
• Adjuvant Taxotere Improves Breast Cancer Survival
• Erbitux Improves Survival in Colorectal Cancer
• Tasigna Approved for Chronic
Hope Shines Brightly for Ovarian Cancer Survivors
By Krishnansu S. Tewari, MD, FACOG, FACS
Ovarian Cancer Advocacy
Poems for Hattie
In the face of the sometimes-unspeakable emotions surrounding a cancer diagnosis, two friends find the words of poets to say what they sometimes cannot, sending verse across the Atlantic and coming to terms with illness, love, and the meaning of their valuable friendship.
Bare Bones Basics
Many women don’t think about bone loss as a major health concern, but learning about this issue—and ways to prevent it—may be more important than we realize.
Bone-Building Recipes
• Italian Sardine Spread
• Ginger Yogurt with Berries
• Spanish Collard Greens
War Room News
• Addition of Erbitux to Chemotherapy Improves Survival in Advanced Non–Small Cell Lung Cancer
• Further Results Show Improved Survival with Picoplatin for Small Cell Lung Cancer
• Further Evidence That Nexavar Improves Liver Cancer Survival Among Different Ethnic Groups
• Evista Approved for Prevention of Breast Cancer
Knowledge is Power
Jaclyn Smith’s diagnosis of breast cancer taught her the value of becoming educated about her health and the power of being lifted by love.
Advances in Breast Cancer Treatment
A Report from the 2007 Annual Meeting of the American Society of Clinical Oncology
Stepping Up Early Detection
Can magnetic resonance imaging improve early detection of breast cancer?
Special Report: Metastatic Breast Cancer
Patients diagnosed with Stage IV or metastatic breast cancers have disease that has spread from the affected breast to one or more distant sites in the body.
Sharsheret
For young Jewish women with breast cancer, common cultural traditions and a sisterhood of support create a welcome home after diagnosis.
Inflammatory Breast Cancer: What You don’t know Can Hurt You
An infrequent but aggressive type of breast cancer requires immediate treatment, but many women have never heard of it.
Inflammatory Breast Cancer Advocacy
Although breast cancer is one of the most widely covered cancers in the media and is represented by innumerable advocacy groups, inflammatory breast cancer (IBC) hasn’t historically received adequate attention, leaving those facing the disease with insufficient resources and avenues of support as they battle a breast cancer with characteristics and treatment protocols that tend to differ significantly from those of other disease types.
It's in the Genes News
• Oncotype DX Influences Breast Cancer Treatment Choices
• Aspirin Protects Against Subset of Colorectal Cancers
• Further Evidence Suggesting Survival Associated with Surgeon Experience in Ovarian Cancer
• Switching from Tamoxifen to Aromatase Inhibitor Improves Survival in Early Breast Cancer
• Femara Reduces Risk of Early Recurrence of Breast Cancer
Leukemia 101
A Basic Guide to Understanding Leukemia
Gleevec and the Chronic Myeloid Leukemia Revolution
How one targeted therapy gives new meaning to “living with cancer”
From Research to Reality
An Interview with Dr. Brian Druker
Cancer’s Glamour Girl
Down-to-earth and down-to-business when it comes to cancer advocacy, Erin Zammett Ruddy discusses her very public journey with chronic myeloid leukemia and why she continues to share her story.
Connecting for a Cure
The Leukemia & Lymphoma Society Is United for Support, Research, and, Ultimately, a Cure
Lifeline
Umbilical cord blood stem cells save lives and provide an important resource for medical research
War Room News
• MRI Screening for Breast Cancer
• Tykerb Approved for Advanced Breast Cancer
• Oncotype DX Effectively Guides Breast Cancer Treatment
• Clinical Trial Evaluating Myocet for Breast Cancer Now Enrolling Patients
• HPV Vaccine Recommended, but Many Unaware of Its Importance
Striking Blows Against Bladder Cancer
Learning about this often-overlooked cancer may save your life.
The Bladder Cancer Web Cafe
Connection and Information The Bladder Cancer WebCafé
Stop Skin Cancer: Before It's More Than Skin Deep
Skin cancer is the most commonly diagnosed cancer in the U.S., with more than one million new cases each year. Although many cases are curable, others are not. Prevention and early detection are the keys to good outcomes.
The Melanoma Research Foundation
One dedicated patient’s dream becomes a reality, as melanoma education, research, and advocacy become the passionate focus for a committed group of survivors, families, and friends.
Bioidentical or Synthetic: New Choices in Hormone Replacement Therapy
New choices in hormone replacement therapy are raising questions about what is safe, what is effective, and what is “natural.”
War Room News
• Femara Improves Cancer-free Survival in Early Breast Cancer
• Six Cycles of Rituxan-CHOP-14 Confirmed as Standard of Care for Elderly with Diffuse Large B-cell Lymphoma
• Herceptin Improves Survival in HER2-positive Early Breast Cancer
• Follow-up Data on Dose-dense Chemotherapy Confirm Benefit in Early Breast Cancer
• Prevalence of HPV in the U.S. Greater than Previously Thought
Weighing the Risks
The issue of body weight is a loaded one. For many of us, it consumes far too much of our energy and attention. In recent years the media have given a lot of attention to the psychological effects that weight and body image issues can have, particularly on women. But despite the unhealthy effect that too much emphasis on an ideal body can have, some attention to body weight—and the associated health issues—is warranted. An unhealthy weight, whether it’s too little weight or too much, can in fact have dramatic effects on health. In addition to increasing the risk of chronic conditions such as diabetes and heart disease, there is evidence that obesity increases the risk of developing certain types of cancer and can decrease survival with cancer.
C3: Colorectal Cancer Coalition
Kate Murphy, director of research communication at the C3: Colorectal Cancer Coalition, was first diagnosed with colon cancer 23 years ago when she was 40. Since then she has had ovarian cancer, breast cancer, and a second colon cancer, but for the past 12 years she has been cancer-free. Kate knows the struggles of the patients and their loved ones who come to the advocacy organization, looking for information and support, and she reflects the organization’s passion as she describes its goals for the visitors to its online community at www.fightcolorectalcancer.org.
Women Have Colons Too
Fewer than 50 percent of women undergo the recommended screening for colorectal cancer in the United States,1 and yet this disease takes the lives of more women each year than ovarian and cervical cancers combined.2 In fact, colorectal cancer is the second-leading cause of cancer death in the United States.3 So why are more women not getting screened? Part of the answer may lie in the misconception that colorectal cancer is a disease that affects only men or in the lack of information about screening guidelines and risk factors for women.
In Their Own Words
Colorectal Cancer Survivor Stories
Highlights from the San Antonio Breast Cancer Symposium
• Decline in Postmenopausal Hormone Use May Explain Drop in Breast Cancer Rate
• Abraxane® Improves Response Rates and Progression-free Survival—with Fewer Side Effects than Taxotere®—in Metastatic Breast Cancer
• Herceptin® and Arimidex® Improves Outcomes in Advanced Breast Cancer
The Verdict Is In: Screening Saves Lives
Breast cancer is diagnosed in more than 200,000 women every year in the United States alone. If detected and treated early, prior to the spread of cancer from the breast to distant sites in the body, cure rates remain high; as the cancer progresses and spreads, long-term survival rates fall dramatically. Therefore it seems only logical that early detection through screening measures—such as mammography (an X-ray of the breast)—will ultimately result in improved survival for women diagnosed with breast cancer.
A Good Prognosis Gets Better: Advances in the Treatment of Early-stage Breast Cancer
Though a diagnosis of breast cancer will always be a shock, women diagnosed with early-stage breast cancer can be reassured by the fact that because the cancer was caught at an early stage, their diagnosis has been delivered when treatment has the best chance of success. Furthermore, recent advances in the treatment of early-stage breast cancer promise greater improvement in patient outcomes.
Gratitude and Grace: The Sheryl Crow Interview
Maybe she’s just a little worn out from her tour schedule—I’ve caught her on a rare day off during month 4 of her Wildflower tour—but a few minutes of conversation reveal the real story, which is much more profound. Her quiet, unhurried, and thoughtful responses reflect someone in touch with the value of her life these days. Her voice, so powerful and beautiful in the music that has earned her nine Grammys and has sold more than 30 million albums, is calm and reflective. Her answers—softened by a slight southern lilt—give me a glimpse of a woman who in recent months has been pushed to come to know herself more intimately than ever before and, having been tested, has found the peace that comes from knowing your own strength and recognizing your own value.
Young Survival Coalition
The Young Survival Coalition (YSC) wants young women with breast cancer to feel empowered. “You are too young for breast cancer is not a diagnosis,” says Michele Przypyszny, YSC’s CEO. “And if you feel your doctor is not addressing your concerns thoroughly, find one who will.” Delivering young women the tools they need to take their breast health into their own hands and recognize that they have the power to advocate for their own well-being is one goal of the organization—the only international, nonprofit group dedicated to the concerns and the issues unique to young women with breast cancer.
Environmental Estrogens
Many variables within a woman’s body contribute to her development of breast cancer; so too, we’re learning, do factors within her environment. We’re zeroing in on the risk factors within the body as research tells us that—among other things—hereditary genes can contribute to the risk of developing the disease. The impact of various environmental factors is still being evaluated, but studies aimed at determining which chemicals and products might contribute to the development of breast cancer are offering clues as to how the environment fits into the cancer-risk puzzle.
Reconstructing Hope: Breast Reconstruction from the Plastic Surgeon’s Point of View
Many of my patients are coping with breast cancer—newly diagnosed, undergoing treatment, or presenting as long-term survivors. Conceptually, everyone understands that there is nothing more important than treating and hopefully curing their cancer and that the side effects are worth bearing for the end result. In actuality, however, not all patients can easily face the reality that some of these important treatments—surgery and radiation included—may leave a breast changed forever: absent, scarred, smaller, or misshapen. They may be facing a new reality when they look at one or both of their breasts.
A Survivor’s Story: For Babies and Balance
For Katherine Jensen, the decision to reconstruct her breasts after cancer treatment was motivated by the many babies who snuggle against her chest. “I am a certified nurse midwife,” Katherine says, “and the thought of a baby snuggling up to my ribcage did not seem right. For me it was not about how I looked in clothes or to anyone else but about how the babies would feel and how I would feel holding them.” Katherine lives in Portland, Oregon, and was diagnosed in April 2001 with Stage IIB invasive ductal carcinoma. In an effort to remove the cancer, doctors performed two lumpectomies on Katherine’s right breast but were unable to get clear margins. She had three of 20 positive nodes and began chemotherapy.
What’s on the Horizon? Microsurgery Options
A cancer diagnosis and all of its related emotions can be an overwhelming experience for many women. The thought of a mastectomy added to the mix can be even more frightening. Loss of a breast might provoke feelings of incompleteness or disfigurement or contribute to a loss of sexuality. But women facing this experience today should know that reconstruction of the breast can be a positive experience that can help restore self-image and self-esteem.
Cancer & Race in America
Cancer remains a significant health problem in African American, Hispanic, and American Indian people despite advances in screening, prevention, and treatment. Women from these populations continue to present with later stages of breast, cervical, and colorectal cancer at diagnosis and have lower survival when compared with White women.
The War Room News
• "Gardasil® Also Likely to Prevent Most Vaginal and Vulvar Cancers"
• "Celebrex® Reduces Pre-cancerous Colorectal Tumors but Increases Cardiovascular Risks"
What Every Woman Should Know About Cancer Screening
Over the past several decades, long-term cancer survival rates have been on the rise. These improved outcomes are largely credited to screening measures for certain types of cancers. In general, cancer that can be detected and treated in its earliest stages, prior to any spread—and often prior to any symptoms—is associated with dramatically higher long-term survival than cancer that is treated once it has spread from its site of origin.2 As a result, screening for common types of cancers gives patients the best chances for early detection and effective treatment, which allow for the best chances for survival. People at a high risk of developing a specific type of cancer may also undergo frequent screening for that type.
Breaking News from ASCO
• "Chemotherapy Benefits Elderly Patients with Non–Small Cell Lung Cancer"
• "Erbitux plus Induction Chemotherapy Results in 100 Percent Response Rate for Head and Neck Cancer"
• "Additional Evidence of Abraxane Activity in Advanced Non–Small Cell Lung Cancer"
• "Vidaza Reduces Need for Transfusions in Myelodysplastic Syndromes"
• "Tykerb Halts Cancer Progression in Advanced Breast Cancer"
• "Panitumumab-targeted Therapy Provides Anticancer Activity in Patients with Advanced Colorectal Cancer"
• "GVAX Achieves Significant Anticancer Responses in CML"
• "Study Continues to Suggest Benefit of Nexavar in the Treatment of Advanced Kidney Cancer"
• "Addition of Erbitux to XELOX Reduces Cancer Progression as First-line Therapy in Metastatic Colorectal Cancer"
Cervical Cancer: From Viruses to Vaccines
For women in the United States, a Papanicolaou (Pap) test has become a standard part of their annual gynecologic exam. Also known as a Pap smear, the test, which was first made public in 1943 when George Papanicolaou and Herbert Traut published their landmark paper Diagnosis of Uterine Cancer by the Vaginal Smear,1 revolutionized the field of cervical cancer prevention by allowing physicians to detect and treat cervical cancer in its earliest stages. In countries with the resources for screening and treatment, widespread cervical cancer screening programs continue to lead to dramatic declines in deaths from this disease.
Breaking the Silence: Telling the Story of Women and Lung Cancer
Though recurrent shoulder pain sent 70-year-old Mary* to see her doctor last year, the Oregon resident never thought she would have reason to be thankful for her arthritis and that doctor’s visit. An X-ray of her shoulder revealed a mass in her lung. Subsequent surgery removed a quarter-sized cancer from the upper lobe of her right lung. Her reaction to the diagnosis: complete surprise. “Colon cancer wouldn’t have surprised me,” she says, but the lung cancer was a shock.
Hear Me Roar: The Changing Face of Lung Cancer
Holly Springs, Georgia, resident Jacqueline Patrick was in a car accident on the day she was diagnosed with lung cancer. Ironically, it was the head-on collision that saved her life. After the moment of impact, Jacqueline immediately had trouble breathing and called 9-1-1. Though it was later revealed that she was not actually hurt in the crash, as a result of the accident she was taken to the hospital for X-rays and scans. It was during these tests that a tumor the size of an orange was discovered in her lower right lobe.
A Legacy of Compassion and Commitment: The Joan Scarangello Foundation to Conquer Lung Cancer
Roxanne Donovan does not hesitate when asked to describe her sister-in-law and closest friend, Joan Scarangello McNeive: “Joan was absolutely magnificent. She was passionately alive and present. She walked through the world with her shoulders back and her head held high. She reveled in the lives of her wide circle of family and friends.”
National Lung Cancer Partnership
Lung cancer strikes down more American women each year than any other cancer. But ask most women if they’ve every worn a ribbon for lung cancer or participated in a walk to show their support for lung cancer survivors, and chances are they probably have not. The National Lung Cancer Partnership (NLCP, formerly Women Against Lung Cancer) is working hard to change that.
Lung Cancer Screening: What's the Standard?
Despite the alarming numbers of women impacted by lung cancer each year in the U.S., there is no consensus today among medical professionals on the benefits of routine screening. This, despite the fact that lung cancer commonly goes undetected until it has progressed to a point that it can no longer be cured. For this reason, the development of accurate screening methods to detect lung cancer early, before symptoms arise, is critical.
subscription only
subscription only
Subscribe
Women & Cancer is the premier women's health and wellness magazine, delivering breaking news about topics critical to women making informed decisions about their own and their family's health and emphasizing cancer prevention, early detection, management, and survivorship.